hMG (Menotropins, Menopur)

A purified mix of FSH and LH. Used in IVF and, in men, alongside HCG to start sperm production when the pituitary doesn't.

Evidence: Extensive clinical research
Half-life: Varies
Sources: 3 cited

Is hMG (Menotropins) FDA-approved?

FDA-approved (Menopur) for fertility treatment.

Overview

Menotropins are purified from the urine of postmenopausal women, whose FSH and LH levels are naturally high. In women they stimulate the ovaries for IVF. In men with hypogonadotropic hypogonadism (the pituitary doesn't send the signal), HCG plus FSH from hMG has been used since the 1980s to start sperm production.

How it works

FSH stimulates egg follicles in women and sperm-producing cells in men; the LH part supports hormone production.

How long does hMG (Menotropins) stay in the body?

It's a mix of hormones, so there isn't one clean number. Levels build over several days of injections.

What it's studied for

IVF ovarian stimulation
Sperm production in men with pituitary or hypothalamic causes

Reported side effects

Ovarian hyperstimulation in women
Injection-site reactions, headache

Sources

The studies and prescribing labels this page is written from.