MIC (Lipotropic Injection)
A clinic shot mixing methionine, inositol and choline (often with B12), sold to support fat metabolism. No good trials show it boosts weight loss.
- Evidence
- Limited human research
- Half-life
- Varies
- Sources
- 2 cited
Is MIC (Lipotropic Injection) FDA-approved?
Made by compounding pharmacies. Not an FDA-approved drug.
Overview
Methionine, inositol and choline are nutrients the liver uses to process and export fat; a severe choline shortage can cause fatty liver. "Lipotropic" shots combine them on the theory that more of these nutrients speeds fat burning. No controlled human trials show extra weight loss from the injections. Oral inositol lowered BMI slightly in a meta-analysis, mostly in women with PCOS.
How it works
Choline and methionine help the liver package fat for export; inositol is involved in insulin signaling.
How long does MIC (Lipotropic Injection) stay in the body?
Not applicable: these are nutrients the body uses continuously.
What it's studied for
- Liver fat metabolism
- PCOS (inositol)
- Weight-loss programs
Reported side effects
- Injection-site soreness
- Nausea or stomach upset (uncommon)
Related: Vitamin B12, Glutathione, Matrixyl, Argireline.
Sources
The studies and prescribing labels this page is written from.
- Inositol supplementation and body mass index: systematic review and meta-analysis. Obes Sci Pract, 2022 PubMed
- Choline: an essential nutrient for public health. Nutr Rev, 2009 PubMed